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Last updated: 2016/10/16
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PRCP purified MaxPab mouse polyclonal antibody (B01P)MaxPab

  • Catalog # : H00005547-B01P
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  • Specification
  • Product Description:
  • Mouse polyclonal antibody raised against a full-length human PRCP protein.
  • Immunogen:
  • PRCP (NP_005031.1, 1 a.a. ~ 496 a.a) full-length human protein.
  • Sequence:
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Quality Control Testing:
  • Antibody reactive against mammalian transfected lysate.
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • Western Blot analysis of PRCP expression in transfected 293T cell line (H00005547-T02) by PRCP MaxPab polyclonal antibody.

    Lane 1: PRCP transfected lysate(54.56 KDa).
    Lane 2: Non-transfected lysate.
  • PDF DownloadProtocol Download
  • Application Image
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 5547
  • Gene Name:
  • PRCP
  • Gene Alias:
  • Gene Description:
  • prolylcarboxypeptidase (angiotensinase C)
  • Gene Summary:
  • The protein encoded by this gene is a lysosomal prolylcarboxypeptidase, which cleaves C-terminal amino acids linked to proline in peptides such as angiotension II, III and des-Arg9-bradykinin. The cleavage occurs at acidic pH, but the enzyme activity is retained with some substrates at neutral pH. This enzyme has been shown to be an activator of the cell matrix-associated prekallikrein. The importance of angiotension II, one of the substrates of this enzyme, in regulating blood pressure and electrolyte balance suggests that this gene may be related to essential hypertension. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq
  • Other Designations:
  • angiotensinase C,lysosomal Pro-x carboxypeptidase,lysosomal carboxypeptidase C,proline carboxypeptidase,prolylcarboxypeptidase,prolylcarboxypeptidase isoform 1 preproprotein
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