PPP3CB (Human) Recombinant Protein (P01)
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More Files
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Specification
Product Description
Human PPP3CB full-length ORF ( AAH28049.1, 1 a.a. - 525 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MAAPEPARAAPPPPPPPPPPPGADRVVKAVPFPPTHRLTSEEVFDLDGIPRVDVLKNHLVKEGRVDEEIALRIINEGAAILRREKTMIEVEAPITVCGDIHGQFFDLMKLFEVGGSPANTRYLFLGDYVDRGYFSIECVLYLWVLKILYPSTLFLLRGNHECRHLTEYFTFKQECKIKYSERVYEACMEAFDSLPLAALLNQQFLCVHGGLSPEIHTLDDIRRLDRFKEPPAFGPMCDLLWSDPSEDFGNEKSQEHFSHNTVRGCSYFYNYPAVCEFLQNNNLLSIIRAHEAQDAGYRMYRKSQTTGFPSLITIFSAPNYLDVYNNKAAVLKYENNVMNIRQFNCSPHPYWLPNFMDVFTWSLPFVGEKVTEMLVNVLSICSDDELMTEGEDQFDVGSAAARKEIIRNKIRAIGKMARVFSVLREESESVLTLKGLTPTGMLPSGVLAGGRQTLQSATVEAIEAEKAIRGFSPPHRICSFEEAKGLDRINERMPPRKDAVQQDGFNSLNTAHATENHGTGNHTAQ
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
85.5
Interspecies Antigen Sequence
Mouse (99); Rat (99)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — PPP3CB
Entrez GeneID
5532GeneBank Accession#
BC028049.1Protein Accession#
AAH28049.1Gene Name
PPP3CB
Gene Alias
CALNA2, CALNB
Gene Description
protein phosphatase 3 (formerly 2B), catalytic subunit, beta isoform
Omim ID
114106Gene Ontology
HyperlinkGene Summary
catalytic subunit
Other Designations
OTTHUMP00000019823|calcineurin A beta|calcineurin A2|protein phosphatase from PCR fragment H32
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Interactome
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Pathway
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Disease
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Publication Reference
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FK506 induces endothelial dysfunction through attenuation of Akt and ERK1/2 independently of calcineurin inhibition and the caspase pathway.
Eguchi R, Kubo S, Ohta T, Kunimasa K, Okada M, Tamaki H, Kaji K, Wakabayashi I, Fujimori Y, Ogawa H.
Cellular Signalling 2013 Sep; 25(9):1731.
Application:WB-Tr, Human, HUVECs.
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FK506 induces endothelial dysfunction through attenuation of Akt and ERK1/2 independently of calcineurin inhibition and the caspase pathway.
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