PPP2R5A purified MaxPab mouse polyclonal antibody (B01P)
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More Files
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human PPP2R5A protein.
Immunogen
PPP2R5A (NP_006234.1, 1 a.a. ~ 486 a.a) full-length human protein.
Sequence
MSSSSPPAGAASAAISASEKVDGFTRKSVRKAQRQKRSQGSSQFRSQGSQAELHPLPQLKDATSNEQQELFCQKLQQCCILFDFMDSVSDLKSKEIKRATLNELVEYVSTNRGVIVESAYSDIVKMISANIFRTLPPSDNPDFDPEEDEPTLEASWPHIQLVYEFFLRFLESPDFQPSIAKRYIDQKFVQQLLELFDSEDPRERDFLKTVLHRIYGKFLGLRAFIRKQINNIFLRFIYETEHFNGVAELLEILGSIINGFALPLKAEHKQFLMKVLIPMHTAKGLALFHAQLAYCVVQFLEKDTTLTEPVIRGLLKFWPKTCSQKEVMFLGEIEEILDVIEPTQFKKIEEPLFKQISKCVSSSHFQVAERALYFWNNEYILSLIEENIDKILPIMFASLYKISKEHWNPTIVALVYNVLKTLMEMNGKLFDDLTSSYKAERQREKKKELEREELWKKLEELKLKKALEKQNSAYNMHSILSNTSAE
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (98); Rat (98)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Tissue lysate)
PPP2R5A MaxPab polyclonal antibody. Western Blot analysis of PPP2R5A expression in human placenta.Western Blot (Cell lysate)
PPP2R5A MaxPab polyclonal antibody. Western Blot analysis of PPP2R5A expression in Jurkat.Western Blot (Transfected lysate)
Western Blot analysis of PPP2R5A expression in transfected 293T cell line (H00005525-T01) by PPP2R5A MaxPab polyclonal antibody.
Lane 1: PPP2R5A transfected lysate(53.46 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — PPP2R5A
Entrez GeneID
5525GeneBank Accession#
NM_006243.2Protein Accession#
NP_006234.1Gene Name
PPP2R5A
Gene Alias
B56A, MGC131915, PR61A
Gene Description
protein phosphatase 2, regulatory subunit B', alpha isoform
Omim ID
601643Gene Ontology
HyperlinkGene Summary
The product of this gene belongs to the phosphatase 2A regulatory subunit B family. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity. This gene encodes an alpha isoform of the regulatory subunit B56 subfamily. [provided by RefSeq
Other Designations
OTTHUMP00000034891|PP2A, B subunit, B' alpha isoform|PP2A, B subunit, B56 alpha isoform|PP2A, B subunit, PR61 alpha isoform|PP2A, B subunit, R5 alpha isoform|protein phosphatase 2, regulatory subunit B (B56), alpha isoform|serine/threonine protein phospha
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Interactome
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Pathway
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Publication Reference
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A novel tumor-derived SGOL1 variant causes abnormal mitosis and unstable chromatid cohesion.
Kahyo T, Iwaizumi M, Shinmura K, Matsuura S, Nakamura T, Watanabe Y, Yamada H, Sugimura H.
Oncogene 2011 Nov; 30(44):4453.
Application:IF, Human, HCT-116 cells.
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A novel tumor-derived SGOL1 variant causes abnormal mitosis and unstable chromatid cohesion.
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