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PPP2R2B (Human) Recombinant Protein (P01)

  • Catalog # : H00005521-P01
  • Visit Frequency :
  • Countries :
  • Specification
  • Product Description:
  • Human PPP2R2B full-length ORF ( AAH31790, 1 a.a. - 443 a.a.) recombinant protein with GST-tag at N-terminal.
  • Sequence:
  • MEEDIDTRKINNSFLRDHSYATEADIISTVEFNHTGELLATGDKGGRVVIFQREQESKNQVHRRGEYNVYSTFQSHEPEFDYLKSLEIEEKINKIRWLPQQNAAYFLLSTNDKTVKLWKVSERDKRPEGYNLKDEEGRLRDPATITTLRVPVLRPMDLMVEATPRRVFANAHTYHINSISVNSDYETYMSADDLRINLWNFEITNQSFNIVDIKPANMEELTEVITAAEFHPHHCNTFVYSSSKGTIRLCDMRASALCDRHTKFFEEPEDPSNRSFFSEIISSISDVKFSHSGRYIMTRDYLTVKVWDLNMENRPIETYQVHDYLRSKLCSLYENDCIFDKFECVWNGSDSVIMTGSYNNFFRMFDRNTKRDVTLEASRENSKPRAILKPRKVCVGGKRRKDEISVDSLDFSKKILHTAWHPSENIIAVAATNNLYIFQDKVN
  • Host:
  • Wheat Germ (in vitro)
  • Theoretical MW (kDa):
  • 74.25
  • Purification:
  • Glutathione Sepharose 4 Fast Flow
  • Quality Control Testing:
  • 12.5% SDS-PAGE Stained with Coomassie Blue.

    QC Testing of H00005521-P01
  • Storage Buffer:
  • 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
  • Storage Instruction:
  • Store at -80°C. Aliquot to avoid repeated freezing and thawing.
  • Note:
  • Best use within three months from the date of receipt of this protein.
  • Applications
  • Enzyme-linked Immunoabsorbent Assay
  • Western Blot (Recombinant protein)
  • Antibody Production
  • Protein Array
  • Application Image
  • Enzyme-linked Immunoabsorbent Assay
  • Western Blot (Recombinant protein)
  • Antibody Production
  • Protein Array
  • Gene Information
  • Entrez GeneID:
  • 5521
  • Gene Name:
  • PPP2R2B
  • Gene Alias:
  • B55-BETA,FLJ95686,MGC24888,PP2A-B55BETA,PP2A-PR55B,PP2AB-BETA,PP2APR55-BETA,PR2AB-BETA,PR2AB55-BETA,PR2APR55-BETA,PR52B,PR55-BETA,SCA12
  • Gene Description:
  • protein phosphatase 2 (formerly 2A), regulatory subunit B, beta isoform
  • Gene Summary:
  • The product of this gene belongs to the phosphatase 2 regulatory subunit B family. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity. This gene encodes a beta isoform of the regulatory subunit B55 subfamily. Defects in this gene cause autosomal dominant spinocerebellar ataxia 12 (SCA12), a disease caused by degeneration of the cerebellum, sometimes involving the brainstem and spinal cord, and in resulting in poor coordination of speech and body movements. Multiple alternatively spliced variants, which encode different isoforms, have been identified for this gene. The 5' UTR of some of these variants includes a CAG trinucleotide repeat sequence (7-28 copies) that can be expanded to 66-78 copies in cases of SCA12. [provided by RefSeq
  • Other Designations:
  • PP2A, subunit B, B-beta isoform,PP2A, subunit B, R2-beta isoform,beta isoform of regulatory subunit B55, protein phosphatase 2,protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), beta isoform,serine/threonine protein phosphatase 2A, 55 kDa
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