PPP2R1B 293T Cell Transient Overexpression Lysate(Denatured)
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More Files
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-PPP2R1B full-length
Host
Human
Theoretical MW (kDa)
66.22
Interspecies Antigen Sequence
Mouse (96); Rat (96)
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-PPP2R1B antibody (H00005519-B01) by Western Blots.
SDS-PAGE Gel
PPP2R1B transfected lysate.
Western Blot
Lane 1: PPP2R1B transfected lysate ( 66.22 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — PPP2R1B
Entrez GeneID
5519GeneBank Accession#
NM_002716Protein Accession#
NP_002707Gene Name
PPP2R1B
Gene Alias
MGC26454, PR65B
Gene Description
protein phosphatase 2 (formerly 2A), regulatory subunit A, beta isoform
Gene Ontology
HyperlinkGene Summary
This gene encodes a constant regulatory subunit of protein phosphatase 2. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The constant regulatory subunit A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit. This gene encodes a beta isoform of the constant regulatory subunit A. Defects in this gene could be the cause of some lung and colon cancers. At least two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
PP2A, subunit A, PR65-beta isoform|PP2A, subunit A, R1-beta isoform|PP2A-A-beta|beta isoform of regulatory subunit A, protein phosphatase 2|protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), beta isoform|protein phosphatase 2, structural/r
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Interactome
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Pathway
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Disease
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