Immunoprecipitation of PPP2R1B transfected lysate using anti-PPP2R1B MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead (U0007), and immunoblotted with PPP2R1B purified MaxPab mouse polyclonal antibody (B01P) (H00005519-B01P).
This gene encodes a constant regulatory subunit of protein phosphatase 2. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The constant regulatory subunit A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit. This gene encodes a beta isoform of the constant regulatory subunit A. Defects in this gene could be the cause of some lung and colon cancers. At least two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
PP2A, subunit A, PR65-beta isoform,PP2A, subunit A, R1-beta isoform,PP2A-A-beta,beta isoform of regulatory subunit A, protein phosphatase 2,protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), beta isoform,protein phosphatase 2, structural/r