PPP2R1B MaxPab rabbit polyclonal antibody (D01)
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human PPP2R1B protein.
Immunogen
PPP2R1B (NP_002707.3, 1 a.a. ~ 601 a.a) full-length human protein.
Sequence
MAGASELGTGPGAAGGDGDDSLYPIAVLIDELRNEDVQLRLNSIKKLSTIALALGVERTRSELLPFLTDTIYDEDEVLLALAEQLGNFTGLVGGPDFAHCLLPPLENLATVEETVVRDKAVESLRQISQEHTPVALEAYFVPLVKRLASGDWFTSRTSACGLFSVCYPRASNAVKAEIRQQFRSLCSDDTPMVRRAAASKLGEFAKVLELDSVKSEIVPLFTSLASDEQDSVRLLAVEACVSIAQLLSQDDLETLVMPTLRQAAEDKSWRVRYMVADRFSELQKAMGPKITLNDLIPAFQNLLKDCEAEVRAAAAHKVKELGENLPIEDRETIIMNQILPYIKELVSDTNQHVKSALASVIMGLSTILGKENTIEHLLPLFLAQLKDECPDVRLNIISNLDCVNEVIGIRQLSQSLLPAIVELAEDAKWRVRLAIIEYMPLLAGQLGVEFFDEKLNSLCMAWLVDHVYAIREAATNNLMKLVQKFGTEWAQNTIVPKVLVMANDPNYLHRMTTLFCINALSEACGQEITTKQMLPIVLKMAGDQVANVRFNVAKSLQKIGPILDTNALQGEVKPVLQKLGQDEDMDVKYFAQEAISVLALA
Host
Rabbit
Reactivity
Human
Interspecies Antigen Sequence
Mouse (96); Rat (96)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
No additive
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Immunoprecipitation
Immunoprecipitation of PPP2R1B transfected lysate using anti-PPP2R1B MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead, and immunoblotted with PPP2R1B purified MaxPab mouse polyclonal antibody (B01P) (H00005519-B01P). -
Gene Info — PPP2R1B
Entrez GeneID
5519GeneBank Accession#
NM_002716Protein Accession#
NP_002707.3Gene Name
PPP2R1B
Gene Alias
MGC26454, PR65B
Gene Description
protein phosphatase 2 (formerly 2A), regulatory subunit A, beta isoform
Gene Ontology
HyperlinkGene Summary
This gene encodes a constant regulatory subunit of protein phosphatase 2. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The constant regulatory subunit A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit. This gene encodes a beta isoform of the constant regulatory subunit A. Defects in this gene could be the cause of some lung and colon cancers. At least two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
PP2A, subunit A, PR65-beta isoform|PP2A, subunit A, R1-beta isoform|PP2A-A-beta|beta isoform of regulatory subunit A, protein phosphatase 2|protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), beta isoform|protein phosphatase 2, structural/r
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Interactome
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Pathway
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Disease
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