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PPP1R8 rabbit monoclonal antibody

  • Catalog # : H00005511-K
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against a human PPP1R8 peptide using ARM Technology.
  • Immunogen:
  • A synthetic peptide of human PPP1R8 is used for rabbit immunization.
    Customer or Abnova will decide on the preferred peptide sequence.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Purification:
  • Protein A
  • Isotype:
  • IgG
  • Quality Control Testing:
  • Antibody reactive against human PPP1R8 peptide by ELISA and mammalian transfected lysate by Western Blot.
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Note:
  • 1. Customer may provide cell or tissue lysate for antibody screening.
    2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.
  • Library Construction:
  • Non-fusion antibody library from rabbit spleen (ARM Technology).
  • Expression:
  • Overexpression vector and transfection into 293H cell line.
  • Deliverable:
  • Up to three rabbit IgG clones of 1 mg each will be delivered to customer.
  • Applications
  • ELISA
  • Application Image
  • Western Blot (Transfected lysate)
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 5511
  • Gene Name:
  • PPP1R8
  • Gene Alias:
  • ARD-1,ARD1,NIPP-1,NIPP1,PRO2047
  • Gene Description:
  • protein phosphatase 1, regulatory (inhibitor) subunit 8
  • Gene Summary:
  • This gene, through alternative splicing, encodes three different isoforms. Two of the protein isoforms encoded by this gene are specific inhibitors of type 1 serine/threonine protein phosphatases and can bind but not cleave RNA. The third protein isoform lacks the phosphatase inhibitory function but is a single-strand endoribonuclease comparable to RNase E of E. coli. This isoform requires magnesium for its function and cleaves specific sites in A+U-rich regions of RNA. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000003847,OTTHUMP00000003848,OTTHUMP00000003849,OTTHUMP00000044938,RNase E,activator of RNA decay,nuclear inhibitor of protein phosphatase-1,nuclear subunit of PP-1,protein phosphatase 1 regulatory inhibitor subunit 8,protein phosphatase 1 regula
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