PPP1R3C (Human) Recombinant Protein (P01)
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Specification
Product Description
Human PPP1R3C full-length ORF ( AAH12625, 1 a.a. - 317 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MSCTRMIQVLDPRPLTSSVMPVDVAMRLCLAHSPPVKSFLGPYDEFQRRHFVNKLKPLKSCLNIKHKAKSQNDWKCSHNQAKKRVVFADSKGLSLTAIHVFSDLPEEPAWDLQFDLLDLNDISSALKHHEEKNLILDFPQPSTDYLSFRSHFQKNFVCLENCSLQERTVTGTVKVKNVSFEKKVQIRITFDSWKNYTDVDCVYMKNVYGGTDSDTFSFAIDLPPVIPTEQKIEFCISYHANGQVFWDNNDGQNYRIVHVQWKPDGVQTQMAPQDCAFHQTSPKTELESTIFGSPRLASGLFPEWQSWGRMENLASYR
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
60.61
Interspecies Antigen Sequence
Mouse (86)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — PPP1R3C
Entrez GeneID
5507GeneBank Accession#
BC012625Protein Accession#
AAH12625Gene Name
PPP1R3C
Gene Alias
PPP1R5
Gene Description
protein phosphatase 1, regulatory (inhibitor) subunit 3C
Omim ID
602999Gene Ontology
HyperlinkGene Summary
Protein phosphatase-1 (PP1; see MIM 176875) participates in the regulation of a wide variety of cellular functions by reversible protein phosphorylation. The ability of PP1 to regulate diverse functions resides in its capacity to interact with a variety of regulatory subunits that may target PP1 to specific subcellular locations, modulate its substrate specificity, and allow its activity to be responsive to extracellular signals. Several targeting subunits of PP1 have been identified, including PPP1R5, the glycogen-binding subunits PPP1R3 (MIM 600917) and PPP1R4, and the nuclear inhibitor of PP1 (PPP1R8; MIM 602636).[supplied by OMIM
Other Designations
OTTHUMP00000020089|Phosphatase 1, regulatory inhibitor subunit 5|protein targeting to glycogen
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Interactome
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Disease
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