Immunoprecipitation of PPP1R3C transfected lysate using anti-PPP1R3C MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead (U0007), and immunoblotted with PPP1R3C purified MaxPab mouse polyclonal antibody (B01P) (H00005507-B01P).
Protein phosphatase-1 (PP1; see MIM 176875) participates in the regulation of a wide variety of cellular functions by reversible protein phosphorylation. The ability of PP1 to regulate diverse functions resides in its capacity to interact with a variety of regulatory subunits that may target PP1 to specific subcellular locations, modulate its substrate specificity, and allow its activity to be responsive to extracellular signals. Several targeting subunits of PP1 have been identified, including PPP1R5, the glycogen-binding subunits PPP1R3 (MIM 600917) and PPP1R4, and the nuclear inhibitor of PP1 (PPP1R8; MIM 602636).[supplied by OMIM
OTTHUMP00000020089,Phosphatase 1, regulatory inhibitor subunit 5,protein targeting to glycogen