PPM1G (Human) Recombinant Protein (Q01)
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More Files
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Specification
Product Description
Human PPM1G partial ORF ( NP_817092, 462 a.a. - 544 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
QRDENGELRLLSSIVEELLDQCLAPDTSGDGTGCDNMTCIIICFKPRNTAELQPESGKRKLEEVLSTEGAEENGNSDKKKKAK
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
34.87
Interspecies Antigen Sequence
Mouse (94); Rat (94)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — PPM1G
Entrez GeneID
5496GeneBank Accession#
NM_177983Protein Accession#
NP_817092Gene Name
PPM1G
Gene Alias
MGC1675, MGC2870, PP2CG, PP2CGAMMA, PPP2CG
Gene Description
protein phosphatase 1G (formerly 2C), magnesium-dependent, gamma isoform
Omim ID
605119Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase is found to be responsible for the dephosphorylation of Pre-mRNA splicing factors, which is important for the formation of functional spliceosome. Studies of a similar gene in mice suggested a role of this phosphatase in regulating cell cycle progression. Alternatively spliced transcript variants encoding the same protein have been described. [provided by RefSeq
Other Designations
OTTHUMP00000123426|PP2C, gamma|protein phosphatase 1C|protein phosphatase 1G|protein phosphatase 2, catalytic subunit, gamma isoform|protein phosphatase 2C gamma isoform|protein phosphatase magnesium-dependent 1 gamma
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Interactome
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Disease
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