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Last updated: 2016/10/23

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PPM1G rabbit monoclonal antibody

  • Catalog # : H00005496-K
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against a human PPM1G peptide using ARM Technology.
  • Immunogen:
  • A synthetic peptide of human PPM1G is used for rabbit immunization.
    Customer or Abnova will decide on the preferred peptide sequence.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Purification:
  • Protein A
  • Isotype:
  • IgG
  • Quality Control Testing:
  • Antibody reactive against human PPM1G peptide by ELISA and mammalian transfected lysate by Western Blot.
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Note:
  • 1. Customer may provide cell or tissue lysate for antibody screening.
    2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.
  • Library Construction:
  • Non-fusion antibody library from rabbit spleen (ARM Technology).
  • Expression:
  • Overexpression vector and transfection into 293H cell line.
  • Deliverable:
  • Up to three rabbit IgG clones of 1 mg each will be delivered to customer.
  • Applications
  • Application Image
  • Western Blot (Transfected lysate)
  • Gene Information
  • Entrez GeneID:
  • 5496
  • GeneBank Accession#:
  • PPM1G
  • Gene Name:
  • PPM1G
  • Gene Alias:
  • Gene Description:
  • protein phosphatase 1G (formerly 2C), magnesium-dependent, gamma isoform
  • Gene Summary:
  • The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase is found to be responsible for the dephosphorylation of Pre-mRNA splicing factors, which is important for the formation of functional spliceosome. Studies of a similar gene in mice suggested a role of this phosphatase in regulating cell cycle progression. Alternatively spliced transcript variants encoding the same protein have been described. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000123426,PP2C, gamma,protein phosphatase 1C,protein phosphatase 1G,protein phosphatase 2, catalytic subunit, gamma isoform,protein phosphatase 2C gamma isoform,protein phosphatase magnesium-dependent 1 gamma
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