PPIB rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human PPIB peptide using ARM Technology.
Immunogen
A synthetic peptide of human PPIB is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human PPIB peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — PPIB
Entrez GeneID
5479GeneBank Accession#
PPIBGene Name
PPIB
Gene Alias
CYP-S1, CYPB, MGC14109, MGC2224, SCYLP
Gene Description
peptidylprolyl isomerase B (cyclophilin B)
Omim ID
123841Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a cyclosporine-binding protein and is mainly located within the endoplasmic reticulum. It is associated with the secretory pathway and released in biological fluids. This protein can bind to cells derived from T- and B-lymphocytes, and may regulate cyclosporine A-mediated immunosuppression. [provided by RefSeq
Other Designations
PPIase|S-cyclophilin|cyclophilin B|cyclophilin-like protein|peptidyl-prolyl cis-trans isomerase B|peptidylprolyl isomerase B|rotamase
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Interactome
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Disease
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