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Last updated: 2017/10/15

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PPAT rabbit monoclonal antibody

  • Catalog # : H00005471-K
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against a human PPAT peptide using ARM Technology.
  • Immunogen:
  • A synthetic peptide of human PPAT is used for rabbit immunization.
    Customer or Abnova will decide on the preferred peptide sequence.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Purification:
  • Protein A
  • Isotype:
  • IgG
  • Quality Control Testing:
  • Antibody reactive against human PPAT peptide by ELISA and mammalian transfected lysate by Western Blot.
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Note:
  • 1. Customer may provide cell or tissue lysate for antibody screening.
    2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.
  • Library Construction:
  • Non-fusion antibody library from rabbit spleen (ARM Technology).
  • Expression:
  • Overexpression vector and transfection into 293H cell line.
  • Deliverable:
  • Up to three rabbit IgG clones of 1 mg each will be delivered to customer.
  • Applications
  • Application Image
  • Western Blot (Transfected lysate)
  • Gene Information
  • Entrez GeneID:
  • 5471
  • GeneBank Accession#:
  • PPAT
  • Gene Name:
  • PPAT
  • Gene Alias:
  • Gene Description:
  • phosphoribosyl pyrophosphate amidotransferase
  • Gene Summary:
  • The protein encoded by this gene is a member of the purine/pyrimidine phosphoribosyltransferase family. This protein is a regulatory allosteric enzyme that catalyzes the first step of de novo purine nucleotide biosynthesis. This gene and PAICS/AIRC, a bifunctional enzyme catalyzing steps six and seven in the purine nucleotide biosynthesis pathway, are located in close proximity on chromosome 4. [provided by RefSeq
  • Other Designations:
  • amidophosphoribosyltransferase,glutamine PRPP amidotransferase,glutamine phosphoribosylpyrophosphatate amidotransferase
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