POR purified MaxPab mouse polyclonal antibody (B01P)
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More Files
- More Functions
Western Blot (Tissue lysate)
POR MaxPab polyclonal antibody. Western Blot analysis of POR expression in human liver.
Western Blot (Transfected lysate)
Western Blot analysis of POR expression in transfected 293T cell line (H00005447-T01) by POR MaxPab polyclonal antibody.
Lane 1: POR transfected lysate(74.8 KDa).
Lane 2: Non-transfected lysate.
Immunofluorescence
Immunofluorescence of purified MaxPab antibody to POR on HeLa cell. [antibody concentration 10 ug/ml]
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human POR protein.
Immunogen
POR (AAH34277.1, 1 a.a. ~ 680 a.a) full-length human protein.
Sequence
MINMGDSHVDTSSTVSEAVAEEVSLFSMTDMILFSLIVGLLTYWFLFRKKKEEVPEFTKIQTLTSSVRESSFVEKMKKTGRNIIVFYGSQTGTAEEFANRLSKDAHRYGMRGMSADPEEYDLADLSSLPEIDNALVVFCMATYGEGDPTDNAQDFYDWLQETDVDLSGVKFAVFGLGNKTYEHFNAMGKYVDKRLEQLGAQRIFELGLGDDDGNLEEDFITWREQFWLAVCEHFGVEATGEESSIRQYELVVHTDIDAAKVYMGEMGRLKSYENQKPPFDAKNPFLAAVTTNRKLNQGTERHLMHLELDISDSKIRYESGDHVAVYPANDSALVNQLGKILGADLDVVMSLNNLDEESNKKHPFPCPTSYRTALTYYLDITNPPRTNVLYELAQYASEPSEQELLRKMASSSGEGKELYLSWVVEARRHILAILQDCPSLRPPIDHLCELLPRLQARYYSIASSSKVHPNSVHICAVVVEYETKAGRINKGVATNWLRAKEPVGENGGRALVPMFVRKSQFRLPFKATTPVIMVGPGTGVAPFIGFIQERAWLRQQGKEVGETLLYYGCRRSDEDYLYREELAQFHRDGALTQLNVAFSREQSHKVYVQHLLKQDREHLWKLIEGGAHIYVCGDARNMARDVQNTFYDIVAELGAMEHAQAVDYIKKLMTKGRYSLDVWS
Host
Mouse
Reactivity
Human
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Tissue lysate)
POR MaxPab polyclonal antibody. Western Blot analysis of POR expression in human liver.Western Blot (Transfected lysate)
Western Blot analysis of POR expression in transfected 293T cell line (H00005447-T01) by POR MaxPab polyclonal antibody.
Lane 1: POR transfected lysate(74.8 KDa).
Lane 2: Non-transfected lysate.
Immunofluorescence
Immunofluorescence of purified MaxPab antibody to POR on HeLa cell. [antibody concentration 10 ug/ml] -
Gene Info — POR
Entrez GeneID
5447GeneBank Accession#
BC034277.1Protein Accession#
AAH34277.1Gene Name
POR
Gene Alias
CPR, CYPOR, DKFZp686G04235, FLJ26468, P450R
Gene Description
P450 (cytochrome) oxidoreductase
Gene Ontology
HyperlinkGene Summary
This gene encodes an endoplasmic reticulum membrane oxidoreductase with an FAD-binding domain and a flavodoxin-like domain. The protein binds two cofactors, FAD and FMN, which allow it to donate electrons directly from NADPH to all microsomal P450 enzymes. Mutations in this gene have been associated with various diseases, including apparent combined P450C17 and P450C21 deficiency, amenorrhea and disordered steroidogenesis, congenital adrenal hyperplasia and Antley-Bixler syndrome. [provided by RefSeq
Other Designations
NADPH-dependent cytochrome P450 reductase|cytochrome P450 reductase
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Interactome
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Disease
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