PON3 293T Cell Transient Overexpression Lysate(Denatured)
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-PON3 full-length
Host
Human
Theoretical MW (kDa)
39.05
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-PON3 antibody (H00005446-B01) by Western Blots.
SDS-PAGE Gel
PON3 transfected lysate.
Western Blot
Lane 1: PON3 transfected lysate ( 39.05 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — PON3
Entrez GeneID
5446GeneBank Accession#
BC070374.1Protein Accession#
AAH70374.1Gene Name
PON3
Gene Alias
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Gene Description
paraoxonase 3
Omim ID
602720Gene Ontology
HyperlinkGene Summary
This gene is a member of the paraoxonase family and lies in a cluster on chromosome 7 with the other two family members. The encoded protein is secreted into the bloodstream and associates with high-density lipoprotein (HDL). The protein also rapidly hydrolyzes lactones and can inhibit the oxidation of low-density lipoprotein (LDL), a function that is believed to slow the initiation and progression of atherosclerosis. Alternatively spliced variants which encode different protein isoforms have been described; however, only one has been fully characterized. [provided by RefSeq
Other Designations
paraoxanase-3|serum paraoxonase/lactonase 3
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Interactome
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Disease
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