PON1 (Human) Recombinant Protein (Q01)
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Specification
Product Description
Human PON1 partial ORF ( NP_000437, 246 a.a. - 355 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
HVYEKHANWTLTPLKSLDFNTLVDNISVDPETGDLWVGCHPNGMKIFFYDSENPPASEVLRIQNILTEEPKVTQVYAENGTVLQGSTVASVYKGKLLIGTVFHKALYCEL
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
37.84
Interspecies Antigen Sequence
Mouse (88); Rat (86)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — PON1
Entrez GeneID
5444GeneBank Accession#
NM_000446Protein Accession#
NP_000437Gene Name
PON1
Gene Alias
ESA, PON
Gene Description
paraoxonase 1
Omim ID
168820Gene Ontology
HyperlinkGene Summary
The enzyme encoded by this gene is an arylesterase that mainly hydrolyzes paroxon to produce p-nitrophenol. Paroxon is an organophosphorus anticholinesterase compound that is produced in vivo by oxidation of the insecticide parathion. Polymorphisms in this gene are a risk factor in coronary artery disease. The gene is found in a cluster of three related paraoxonase genes at 7q21.3. [provided by RefSeq
Other Designations
arylesterase B-type|esterase A|paraoxonase B-type|serum aryldiakylphosphatase
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Interactome
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Pathway
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Disease
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