POLRMT (Human) Recombinant Protein (Q02)
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More Files
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Specification
Product Description
Human POLRMT partial ORF ( NP_005026.2, 1 a.a. - 100 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MSALCWGRGAAGLKRALRPCGRPGLPGKEGTAGGVCGPRRSSSASPQEQDQDRRKDWGHVELLEVLQARVRQLQAESVSEVVVNRVDVARLPECGSGDGS
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
36.74
Interspecies Antigen Sequence
Mouse (57); Rat (53)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — POLRMT
Entrez GeneID
5442GeneBank Accession#
NM_005035Protein Accession#
NP_005026.2Gene Name
POLRMT
Gene Alias
APOLMT, MTRNAP, MTRPOL, h-mtRPOL
Gene Description
polymerase (RNA) mitochondrial (DNA directed)
Omim ID
601778Gene Ontology
HyperlinkGene Summary
This gene encodes a mitochondrial DNA-directed RNA polymerase. The gene product is responsible for mitochondrial gene expression as well as for providing RNA primers for initiation of replication of the mitochondrial genome. Although this polypeptide has the same function as the three nuclear DNA-directed RNA polymerases, it is more closely related to RNA polymerases of phage and mitochondrial polymerases of lower eukaryotes. [provided by RefSeq
Other Designations
mitochondrial DNA-directed RNA polymerase
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Interactome
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Disease
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