POLRMT monoclonal antibody (M04), clone 2H7
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More Files
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant POLRMT.
Immunogen
POLRMT (NP_005026.2, 1 a.a. ~ 100 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
MSALCWGRGAAGLKRALRPCGRPGLPGKEGTAGGVCGPRRSSSASPQEQDQDRRKDWGHVELLEVLQARVRQLQAESVSEVVVNRVDVARLPECGSGDGS
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (57); Rat (53)
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (36.74 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged POLRMT is 0.3 ng/ml as a capture antibody.ELISA
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Gene Info — POLRMT
Entrez GeneID
5442GeneBank Accession#
NM_005035Protein Accession#
NP_005026.2Gene Name
POLRMT
Gene Alias
APOLMT, MTRNAP, MTRPOL, h-mtRPOL
Gene Description
polymerase (RNA) mitochondrial (DNA directed)
Omim ID
601778Gene Ontology
HyperlinkGene Summary
This gene encodes a mitochondrial DNA-directed RNA polymerase. The gene product is responsible for mitochondrial gene expression as well as for providing RNA primers for initiation of replication of the mitochondrial genome. Although this polypeptide has the same function as the three nuclear DNA-directed RNA polymerases, it is more closely related to RNA polymerases of phage and mitochondrial polymerases of lower eukaryotes. [provided by RefSeq
Other Designations
mitochondrial DNA-directed RNA polymerase
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Interactome
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Disease
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