POLRMT rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human POLRMT peptide using ARM Technology.
Immunogen
A synthetic peptide of human POLRMT is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human POLRMT peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — POLRMT
Entrez GeneID
5442GeneBank Accession#
POLRMTGene Name
POLRMT
Gene Alias
APOLMT, MTRNAP, MTRPOL, h-mtRPOL
Gene Description
polymerase (RNA) mitochondrial (DNA directed)
Omim ID
601778Gene Ontology
HyperlinkGene Summary
This gene encodes a mitochondrial DNA-directed RNA polymerase. The gene product is responsible for mitochondrial gene expression as well as for providing RNA primers for initiation of replication of the mitochondrial genome. Although this polypeptide has the same function as the three nuclear DNA-directed RNA polymerases, it is more closely related to RNA polymerases of phage and mitochondrial polymerases of lower eukaryotes. [provided by RefSeq
Other Designations
mitochondrial DNA-directed RNA polymerase
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Interactome
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Disease
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