POLR2I rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human POLR2I peptide using ARM Technology.
Immunogen
A synthetic peptide of human POLR2I is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human POLR2I peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — POLR2I
Entrez GeneID
5438GeneBank Accession#
POLR2IGene Name
POLR2I
Gene Alias
RPB9, hRPB14.5
Gene Description
polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa
Omim ID
180662Gene Ontology
HyperlinkGene Summary
This gene encodes a subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. This subunit, in combination with two other polymerase subunits, forms the DNA binding domain of the polymerase, a groove in which the DNA template is transcribed into RNA. The product of this gene has two zinc finger motifs with conserved cysteines and the subunit does possess zinc binding activity. [provided by RefSeq
Other Designations
DNA directed RNA polymerase II polypeptide I|polymerase (RNA) II (DNA directed) polypeptide I (14.5kD)
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Interactome
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Pathway
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