POLR2E MaxPab rabbit polyclonal antibody (D01)
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More Files
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Immunoprecipitation
Immunoprecipitation of POLR2E transfected lysate using anti-POLR2E MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead, and immunoblotted with POLR2E purified MaxPab mouse polyclonal antibody (B01P) (H00005434-B01P).
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human POLR2E protein.
Immunogen
POLR2E (NP_002686.2, 1 a.a. ~ 210 a.a) full-length human protein.
Sequence
MDDEEETYRLWKIRKTIMQLCHDRGYLVTQDELDQTLEEFKAQFGDKPSEGRPRRTDLTVLVAHNDDPTDQMFVFFPEEPKVGIKTIKVYCQRMQEENITRALIVVQQGMTPSAKQSLVDMAPKYILEQFLQQELLINITEHELVPEHVVMTKEEVTELLARYKLRENQLPRIQAGDPVARYFGIKRGQVVKIIRPSETAGRYITYRLVQ
Host
Rabbit
Reactivity
Human
Interspecies Antigen Sequence
Mouse (99); Rat (99)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
No additive
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Immunoprecipitation
Immunoprecipitation of POLR2E transfected lysate using anti-POLR2E MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead, and immunoblotted with POLR2E purified MaxPab mouse polyclonal antibody (B01P) (H00005434-B01P). -
Gene Info — POLR2E
Entrez GeneID
5434GeneBank Accession#
NM_002695.2Protein Accession#
NP_002686.2Gene Name
POLR2E
Gene Alias
RPABC1, RPB5, XAP4, hRPB25, hsRPB5
Gene Description
polymerase (RNA) II (DNA directed) polypeptide E, 25kDa
Omim ID
180664Gene Ontology
HyperlinkGene Summary
This gene encodes the fifth largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. This subunit is shared by the other two DNA-directed RNA polymerases and is present in two-fold molar excess over the other polymerase subunits. An interaction between this subunit and a hepatitis virus transactivating protein has been demonstrated, suggesting that interaction between transcriptional activators and the polymerase can occur through this subunit. A pseudogene is located on chromosome 11. [provided by RefSeq
Other Designations
DNA directed RNA polymerase II 23 kda polypeptide|DNA directed RNA polymerase II polypeptide E|polymerase (RNA) II (DNA directed) polypeptide E (25kD)
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Interactome
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Pathway
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Disease
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