POLR2C monoclonal antibody (M01), clone 1C11
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More Files
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Specifications
Product Description
Mouse monoclonal antibody raised against a full-length recombinant POLR2C.
Immunogen
POLR2C (AAH28157, 1 a.a. ~ 275 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
MPYANQPTVRITELTDENVKFIIENTDLAVANSIRRVFIAEVPIIAIDWVQIDANSSVLHDEFIAHRLGLIPLISDDIVDKLQYSRDCTCEEFCPECSVEFTLDVRCNEDQTRHVTSRDLISNSPRVIPVTSRNRDNDPNDYVEQDDILIVKLRKGQELRLRAYAKKGFGKEHAKWNPTAGVAFEYDPDNALRHTVYPKPEEWPKSEYSELDEDESQAPYDPNGKPERFYYNVESCGSLRPETIVLSALSGLKKKLSDLQTQLSHEIQSDVLTIN
Host
Mouse
Reactivity
Human
Isotype
IgG1 Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged POLR2C is 0.3 ng/ml as a capture antibody.ELISA
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Gene Info — POLR2C
Entrez GeneID
5432GeneBank Accession#
BC028157Protein Accession#
AAH28157Gene Name
POLR2C
Gene Alias
RPB3, RPB31, hRPB33, hsRPB3
Gene Description
polymerase (RNA) II (DNA directed) polypeptide C, 33kDa
Omim ID
180663Gene Ontology
HyperlinkGene Summary
This gene encodes the third largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. The product of this gene contains a cysteine rich region and exists as a heterodimer with another polymerase subunit, POLR2J. These two subunits form a core subassembly unit of the polymerase. A pseudogene has been identified on chromosome 21. [provided by RefSeq
Other Designations
DNA directed RNA polymerase II polypeptide C|RNA polymerase II subunit 3|polymerase (RNA) II (DNA directed) polypeptide C (33kD)
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Interactomes
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Pathways
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Diseases
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