POLR2C rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human POLR2C peptide using ARM Technology.
Immunogen
A synthetic peptide of human POLR2C is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human POLR2C peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — POLR2C
Entrez GeneID
5432GeneBank Accession#
POLR2CGene Name
POLR2C
Gene Alias
RPB3, RPB31, hRPB33, hsRPB3
Gene Description
polymerase (RNA) II (DNA directed) polypeptide C, 33kDa
Omim ID
180663Gene Ontology
HyperlinkGene Summary
This gene encodes the third largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. The product of this gene contains a cysteine rich region and exists as a heterodimer with another polymerase subunit, POLR2J. These two subunits form a core subassembly unit of the polymerase. A pseudogene has been identified on chromosome 21. [provided by RefSeq
Other Designations
DNA directed RNA polymerase II polypeptide C|RNA polymerase II subunit 3|polymerase (RNA) II (DNA directed) polypeptide C (33kD)
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