POLH (Human) IP-WB Antibody Pair
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Specification
Product Description
This IP-WB antibody pair set comes with one antibody for immunoprecipitation and another to detect the precipitated protein in western blot.
Reactivity
Human
Quality Control Testing
Immunoprecipitation-Western Blot (IP-WB)
Immunoprecipitation of POLH transfected lysate using rabbit polyclonal anti-POLH and Protein A Magnetic Bead (U0007), and immunoblotted with mouse purified polyclonal anti-POLH.
Supplied Product
Antibody pair set content:
1. Antibody pair for IP: rabbit polyclonal anti-POLH (300 ul)
2. Antibody pair for WB: mouse purified polyclonal anti-POLH (50 ug)
Storage Instruction
Store reagents of the antibody pair set at -20°C or lower. Please aliquot to avoid repeated freeze thaw cycle. Reagents should be returned to -20°C storage immediately after use.
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Applications
Immunoprecipitation-Western Blot
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Gene Info — POLH
Entrez GeneID
5429Gene Name
POLH
Gene Alias
FLJ16395, FLJ21978, RAD30, RAD30A, XP-V, XPV
Gene Description
polymerase (DNA directed), eta
Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the Y family of specialized DNA polymerases. It copies undamaged DNA with a lower fidelity than other DNA-directed polymerases. However, it accurately replicates UV-damaged DNA; when thymine dimers are present, this polymerase inserts the complementary nucleotides in the newly synthesized DNA, thereby bypassing the lesion and suppressing the mutagenic effect of UV-induced DNA damage. This polymerase is thought to be involved in hypermutation during immunoglobulin class switch recombination. Mutations in this gene result in XPV, a variant type of xeroderma pigmentosum. [provided by RefSeq
Other Designations
OTTHUMP00000016478|OTTHUMP00000039868
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Interactome
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Disease
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