POLH (Human) IP-WB Antibody Pair

Catalog # H00005429-PW1

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Size:1 Set
Price: USD $ 607.00
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Immunoprecipitation of POLH transfected lysate using rabbit polyclonal anti-POLH and Protein A Magnetic Bead (U0007), and immunoblotted with mouse purified polyclonal anti-POLH.

  • Specification

    Product Description

    This IP-WB antibody pair set comes with one antibody for immunoprecipitation and another to detect the precipitated protein in western blot.

    Reactivity

    Human

    Quality Control Testing

    Immunoprecipitation-Western Blot (IP-WB)

    Immunoprecipitation of POLH transfected lysate using rabbit polyclonal anti-POLH and Protein A Magnetic Bead (U0007), and immunoblotted with mouse purified polyclonal anti-POLH.

    Supplied Product

    Antibody pair set content:
    1. Antibody pair for IP: rabbit polyclonal anti-POLH (300 ul)
    2. Antibody pair for WB: mouse purified polyclonal anti-POLH (50 ug)

    Storage Instruction

    Store reagents of the antibody pair set at -20°C or lower. Please aliquot to avoid repeated freeze thaw cycle. Reagents should be returned to -20°C storage immediately after use.

  • Applications

    Immunoprecipitation-Western Blot

  • Gene Info — POLH

    Entrez GeneID

    5429

    Gene Name

    POLH

    Gene Alias

    FLJ16395, FLJ21978, RAD30, RAD30A, XP-V, XPV

    Gene Description

    polymerase (DNA directed), eta

    Omim ID

    278750 603968

    Gene Ontology

    Hyperlink

    Gene Summary

    This gene encodes a member of the Y family of specialized DNA polymerases. It copies undamaged DNA with a lower fidelity than other DNA-directed polymerases. However, it accurately replicates UV-damaged DNA; when thymine dimers are present, this polymerase inserts the complementary nucleotides in the newly synthesized DNA, thereby bypassing the lesion and suppressing the mutagenic effect of UV-induced DNA damage. This polymerase is thought to be involved in hypermutation during immunoglobulin class switch recombination. Mutations in this gene result in XPV, a variant type of xeroderma pigmentosum. [provided by RefSeq

    Other Designations

    OTTHUMP00000016478|OTTHUMP00000039868

  • Interactome
  • Disease
Contact Info
  • +1-909-264-1399
    +1-909-992-0619
    Toll Free : +1-877-853-6098
  • +1-909-992-3401
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