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Last updated: 2017/6/25

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POLG Pre-design Chimera RNAi

  • Catalog # : H00005428-R01
  • Visit Frequency :
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  • Specification
  • Product Description:
  • Homo sapiens polymerase (DNA directed), gamma (POLG), mRNA.
  • Reactivity:
  • Human
  • Supplied Product:
  • DEPC water
  • Target Refseq:
  • NM_002693
  • Storage Instruction:
  • Store at -20°C, do not exceed 4 - 5 freeze-thaw cycles to ensure product integrity.
  • Note:
  • Position of the Chimera RNAi.

  • Publication Reference
  • Applications
  • RNAi Knockdown
  • Application Image
  • RNAi Knockdown
  • Gene Information
  • Entrez GeneID:
  • 5428
  • Gene Name:
  • POLG
  • Gene Alias:
  • FLJ27114,MDP1,PEO,POLG1,POLGA,SANDO,SCAE
  • Gene Description:
  • polymerase (DNA directed), gamma
  • Gene Summary:
  • Mitochondrial DNA polymerase is heterotrimeric, consisting of a homodimer of accessory subunits plus a catalytic subunit. The protein encoded by this gene is the catalytic subunit of mitochondrial DNA polymerase. The encoded protein contains a polyglutamine tract near its N-terminus that may be polymorphic. Defects in this gene are a cause of progressive external ophthalmoplegia with mitochondrial DNA deletions 1 (PEOA1), sensory ataxic neuropathy dysarthria and ophthalmoparesis (SANDO), Alpers-Huttenlocher syndrome (AHS), and mitochondrial neurogastrointestinal encephalopathy syndrome (MNGIE). Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq
  • Other Designations:
  • DNA polymerase gamma,DNA polymerase subunit gamma-1,PolG, catalytic subunit,PolG-alpha,mitochondrial DNA polymerase catalytic subunit
  • Gene Pathway
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