POLB (Human) Recombinant Protein (P01)
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More Files
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Specification
Product Description
Human POLB full-length ORF ( AAI06910.1, 1 a.a. - 335 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MSKRKAPQETLNGGITDMLTELANFEKNVSQAIHKYNAYRKAASVIAKYPHKIKSGAEAKKLPGVGTKIAEKIDEFLATGKLRKLEKIRQDDTSSSINFLTRVSGIGPSAARKFVDEGIKTLEDLRKNEDKLNHHQRIGLKYFGDFEKRIPREEMLQMQDIVLNEVKKVDSEYIATVCGSFRRGAESSGDMDVLLTHPSFTSESTKQPKLLHQVVEQLQKVHFITDTLSKGETKFMGVCQLPSKNDEKEYPHRRIDIRLIPKDQYYCGVLYFTGSDIFNKNMRAHALEKGFTINEYTIRPLGVTGVAGEPLPVDSEKDIFDYIQWKYREPKDRSE
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
64.6
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — POLB
Entrez GeneID
5423GeneBank Accession#
BC106909.1Protein Accession#
AAI06910.1Gene Name
POLB
Gene Alias
MGC125976
Gene Description
polymerase (DNA directed), beta
Omim ID
174760Gene Ontology
HyperlinkGene Summary
In eukaryotic cells, DNA polymerase beta (POLB) performs base excision repair (BER) required for DNA maintenance, replication, recombination, and drug resistance. Also see POLA (MIM 312040).[supplied by OMIM
Other Designations
DNA pol beta|DNA polymerase beta subunit
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Interactome
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Pathway
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Disease
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