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Last updated: 2016/12/4
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SEPT5 MaxPab rabbit polyclonal antibody (D01)MaxPab

  • Catalog # : H00005413-D01
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against a full-length human SEPT5 protein.
  • Immunogen:
  • SEPT5 (NP_002679.2, 1 a.a. ~ 369 a.a) full-length human protein.
  • Sequence:
  • MSTGLRYKSKLATPEDKQDIDKQYVGFATLPNQVHRKSVKKGFDFTLMVAGESGLGKSTLVHSLFLTDLYKDRKLLSAEERISQTVEILKHTVDIEEKGVKLKLTIVDTPGFGDAVNNTECWKPITDYVDQQFEQYFRDESGLNRKNIQDNRVHCCLYFISPFGHGLRPVDVGFMKALHEKVNIVPLIAKADCLVPSEIRKLKERIREEIDKFGIHVYQFPECDSDEDEDFKQQDRELKESAPFAVIGSNTVVEAKGQRVRGRLYPWGIVEVENQAHCDFVKLRNMLIRTHMHDLKDVTCDVHYENYRAHCIQQMTSKLTQDSRMESPIPILPLPTPDAETEKLIRMKDEELRRMQEMLQRMKQQMQDQ
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Quality Control Testing:
  • Antibody reactive against mammalian transfected lysate.
  • Storage Buffer:
  • No additive
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • SEPT5 MaxPab rabbit polyclonal antibody. Western Blot analysis of SEPT5 expression in HeLa.
  • PDF DownloadProtocol Download
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • Western Blot analysis of SEPT5 expression in transfected 293T cell line (H00005413-T04) by SEPT5 MaxPab polyclonal antibody.

    Lane 1: SEPT5 transfected lysate(42.8 KDa).
    Lane 2: Non-transfected lysate.
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  • Immunoprecipitation
  • Immunoprecipitation
  • Immunoprecipitation of SEPT5 transfected lysate using anti-SEPT5 MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead (U0007), and immunoblotted with SEPT5 purified MaxPab mouse polyclonal antibody (B02P) (H00005413-B02P).
  • PDF DownloadProtocol Download
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 5413
  • Gene Name:
  • SEPT5
  • Gene Alias:
  • CDCREL,CDCREL-1,CDCREL1,H5,PNUTL1
  • Gene Description:
  • septin 5
  • Gene Summary:
  • This gene is a member of the septin gene family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. This gene is mapped to 22q11, the region frequently deleted in DiGeorge and velocardiofacial syndromes. A translocation involving the MLL gene and this gene has also been reported in patients with acute myeloid leukemia. Two transcripts of this gene, a major one of 2.2 kb and a minor one of 3.5 kb, have been observed. The 2.2 kb form results from the utilization of a non-consensus polyA signal (AACAAT). In the absence of polyadenylation from this imperfect site, the consensus polyA signal of the downstream neighboring gene (GP1BB; platelet glycoprotein Ib) is used, resulting in the 3.5 kb transcript. An alternatively spliced transcript variant with a different 5' end has also been identified, but its full-length nature has not been completely determined. [provided by RefSeq
  • Other Designations:
  • cell division control related protein 1,peanut-like 1,platelet glycoprotein Ib beta chain
  • Gene Pathway
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