SEPT5 MaxPab rabbit polyclonal antibody (D01)
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More Files
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human SEPT5 protein.
Immunogen
SEPT5 (NP_002679.2, 1 a.a. ~ 369 a.a) full-length human protein.
Sequence
MSTGLRYKSKLATPEDKQDIDKQYVGFATLPNQVHRKSVKKGFDFTLMVAGESGLGKSTLVHSLFLTDLYKDRKLLSAEERISQTVEILKHTVDIEEKGVKLKLTIVDTPGFGDAVNNTECWKPITDYVDQQFEQYFRDESGLNRKNIQDNRVHCCLYFISPFGHGLRPVDVGFMKALHEKVNIVPLIAKADCLVPSEIRKLKERIREEIDKFGIHVYQFPECDSDEDEDFKQQDRELKESAPFAVIGSNTVVEAKGQRVRGRLYPWGIVEVENQAHCDFVKLRNMLIRTHMHDLKDVTCDVHYENYRAHCIQQMTSKLTQDSRMESPIPILPLPTPDAETEKLIRMKDEELRRMQEMLQRMKQQMQDQ
Host
Rabbit
Reactivity
Human
Interspecies Antigen Sequence
Mouse (99)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
No additive
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Cell lysate)
SEPT5 MaxPab rabbit polyclonal antibody. Western Blot analysis of SEPT5 expression in HeLa.Western Blot (Transfected lysate)
Western Blot analysis of SEPT5 expression in transfected 293T cell line (H00005413-T04) by SEPT5 MaxPab polyclonal antibody.
Lane 1: SEPT5 transfected lysate(42.8 KDa).
Lane 2: Non-transfected lysate.
Immunoprecipitation
Immunoprecipitation of SEPT5 transfected lysate using anti-SEPT5 MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead, and immunoblotted with SEPT5 purified MaxPab mouse polyclonal antibody (B02P) (H00005413-B02P).Immunofluorescence
Immunofluorescence of purified MaxPab antibody to SEPT5 on HeLa cell. [antibody concentration 20 ug/ml] -
Gene Info — SEPT5
Entrez GeneID
5413GeneBank Accession#
NM_002688Protein Accession#
NP_002679.2Gene Name
SEPT5
Gene Alias
CDCREL, CDCREL-1, CDCREL1, H5, PNUTL1
Gene Description
septin 5
Omim ID
602724Gene Ontology
HyperlinkGene Summary
This gene is a member of the septin gene family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. This gene is mapped to 22q11, the region frequently deleted in DiGeorge and velocardiofacial syndromes. A translocation involving the MLL gene and this gene has also been reported in patients with acute myeloid leukemia. Two transcripts of this gene, a major one of 2.2 kb and a minor one of 3.5 kb, have been observed. The 2.2 kb form results from the utilization of a non-consensus polyA signal (AACAAT). In the absence of polyadenylation from this imperfect site, the consensus polyA signal of the downstream neighboring gene (GP1BB; platelet glycoprotein Ib) is used, resulting in the 3.5 kb transcript. An alternatively spliced transcript variant with a different 5' end has also been identified, but its full-length nature has not been completely determined. [provided by RefSeq
Other Designations
cell division control related protein 1|peanut-like 1|platelet glycoprotein Ib beta chain
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