PNMT (Human) Recombinant Protein (P01)
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More Files
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Specification
Product Description
Human PNMT full-length ORF ( NP_002677.1, 1 a.a. - 282 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MSGADRSPNAGAAPDSAPGQAAVASAYQRFEPRAYLRNNYAPPRGDLCNPNGVGPWKLRCLAQTFATGEVSGRTLIDIGSGPTVYQLLSACSHFEDITMTDFLEVNRQELGRWLQEEPGAFNWSMYSQHACLIEGKGECWQDKERQLRARVKRVLPIDVHQPQPLGAGSPAPLPADALVSAFCLEAVSPDLASFQRALDHITTLLRPGGHLLLIGALEESWYLAGEARLTVVPVSEEEVREALVRSGYKVRDLRTYIMPAHLQTGVDDVKGVFFAWAQKVGL
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
57.3
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — PNMT
Entrez GeneID
5409GeneBank Accession#
NM_002686.2Protein Accession#
NP_002677.1Gene Name
PNMT
Gene Alias
MGC34570, PENT, PNMTase
Gene Description
phenylethanolamine N-methyltransferase
Omim ID
171190Gene Ontology
HyperlinkGene Summary
The product of this gene catalyzes the last step of the catecholamine biosynthesis pathway, which methylates norepinephrine to form epinephrine (adrenaline). The enzyme also has beta-carboline 2N-methyltransferase activity. This gene is thought to play a key step in regulating epinephrine production. [provided by RefSeq
Other Designations
OTTHUMP00000164271|noradrenaline N-methyltransferase|phenylethanolamine N-methylase
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Interactome
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Pathway
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Disease
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