PNMT monoclonal antibody (M06), clone 3G4
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant PNMT.
Immunogen
PNMT (NP_002677, 1 a.a. ~ 110 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
MSGADRSPNAGAAPDSAPGQAAVASAYQRFEPRAYLRNNYAPPRGDLCNPNGVGPWKLRCLAQTFATGEVSGRTLIDIGSGPTVYQLLSACSHFEDITMTDFLEVNRQEL
Host
Mouse
Reactivity
Human
Isotype
IgG2b Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Immunoprecipitation
Immunoprecipitation of PNMT transfected lysate using anti-PNMT monoclonal antibody and Protein A Magnetic Bead, and immunoblotted with PNMT MaxPab rabbit polyclonal antibody.ELISA
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Gene Info — PNMT
Entrez GeneID
5409GeneBank Accession#
NM_002686Protein Accession#
NP_002677Gene Name
PNMT
Gene Alias
MGC34570, PENT, PNMTase
Gene Description
phenylethanolamine N-methyltransferase
Omim ID
171190Gene Ontology
HyperlinkGene Summary
The product of this gene catalyzes the last step of the catecholamine biosynthesis pathway, which methylates norepinephrine to form epinephrine (adrenaline). The enzyme also has beta-carboline 2N-methyltransferase activity. This gene is thought to play a key step in regulating epinephrine production. [provided by RefSeq
Other Designations
OTTHUMP00000164271|noradrenaline N-methyltransferase|phenylethanolamine N-methylase
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Interactome
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Pathway
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Disease
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