PNMT MaxPab rabbit polyclonal antibody (D01)
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More Files
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human PNMT protein.
Immunogen
PNMT (NP_002677.1, 1 a.a. ~ 282 a.a) full-length human protein.
Sequence
MSGADRSPNAGAAPDSAPGQAAVASAYQRFEPRAYLRNNYAPPRGDLCNPNGVGPWKLRCLAQTFATGEVSGRTLIDIGSGPTVYQLLSACSHFEDITMTDFLEVNRQELGRWLQEEPGAFNWSMYSQHACLIEGKGECWQDKERQLRARVKRVLPIDVHQPQPLGAGSPAPLPADALVSAFCLEAVSPDLASFQRALDHITTLLRPGGHLLLIGALEESWYLAGEARLTVVPVSEEEVREALVRSGYKVRDLRTYIMPAHLQTGVDDVKGVFFAWAQKVGL
Host
Rabbit
Reactivity
Human
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
No additive
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of PNMT expression in transfected 293T cell line (H00005409-T02) by PNMT MaxPab polyclonal antibody.
Lane 1: PNMT transfected lysate(30.90 KDa).
Lane 2: Non-transfected lysate.
Immunoprecipitation
Immunoprecipitation of PNMT transfected lysate using anti-PNMT MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead, and immunoblotted with PNMT MaxPab mouse polyclonal antibody (B01) (H00005409-B01). -
Gene Info — PNMT
Entrez GeneID
5409GeneBank Accession#
NM_002686.2Protein Accession#
NP_002677.1Gene Name
PNMT
Gene Alias
MGC34570, PENT, PNMTase
Gene Description
phenylethanolamine N-methyltransferase
Omim ID
171190Gene Ontology
HyperlinkGene Summary
The product of this gene catalyzes the last step of the catecholamine biosynthesis pathway, which methylates norepinephrine to form epinephrine (adrenaline). The enzyme also has beta-carboline 2N-methyltransferase activity. This gene is thought to play a key step in regulating epinephrine production. [provided by RefSeq
Other Designations
OTTHUMP00000164271|noradrenaline N-methyltransferase|phenylethanolamine N-methylase
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Interactome
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Pathway
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Disease
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