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PMS2 293T Cell Transient Overexpression Lysate(Denatured)

  • Catalog # : H00005395-T01
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  • Specification
  • Transfected Cell Line:
  • 293T
  • Plasmid:
  • pCMV-PMS2 full-length
  • Host:
  • Human
  • Theoretical MW (kDa):
  • 94.93
  • Quality Control Testing:
  • Transient overexpression cell lysate was tested with Anti-PMS2 antibody (H00005395-B01) by Western Blots.
    SDS-PAGE Gel
    QC Testing of H00005395-T01
    PMS2 transfected lysate.
    Western Blot
    QC Testing of H00005395-T01
    Lane 1: PMS2 transfected lysate ( 94.93 KDa)
    Lane 2: Non-transfected lysate.
  • Storage Buffer:
  • 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
  • Storage Instruction:
  • Store at -80°C. Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Western Blot
  • Application Image
  • Western Blot
  • Gene Information
  • Entrez GeneID:
  • 5395
  • Gene Name:
  • PMS2
  • Gene Alias:
  • HNPCC4,PMS2CL,PMSL2
  • Gene Description:
  • PMS2 postmeiotic segregation increased 2 (S. cerevisiae)
  • Gene Summary:
  • This gene is one of the PMS2 gene family members found in clusters on chromosome 7. The product of this gene is involved in DNA mismatch repair. It forms a heterodimer with MLH1 and this complex interacts with other complexes bound to mismatched bases. Mutations in this gene are associated with hereditary nonpolyposis colorectal cancer, Turcot syndrome, and are a cause of supratentorial primitive neuroectodermal tumors. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq
  • Other Designations:
  • DNA mismatch repair protein,H_DJ0042M02.9,PMS2 postmeiotic segregation increased 2,mismatch repair endonuclease,postmeiotic segregation increased 2
  • Gene Pathway
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