PMS1 (Human) Recombinant Protein (P01)
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More Files
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Specification
Product Description
Human PMS1 full-length ORF ( AAH08410, 1 a.a. - 166 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MKQLPAATVRLLSSSQIITSVVSVVKELIENSLDAGATSVDVKLENYGFDKIEVRDNGEGIKAVDAPVMAMKYYTSKINSHEDLENLTTYGFRGEALGSICCIAEVLITTRTAADNFSTQYVLDGSGHILSQKPSHLGQGKKVALYTNILYLFCLNCWFKKKKVTR
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
44
Interspecies Antigen Sequence
Mouse (85); Rat (84)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
In NCBI database, the accession number (AAH08410) of this protein had been removed, and indicated as obsolete version. However, this product is still available in our catalog for specific research purpose. -
Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — PMS1
Entrez GeneID
5378GeneBank Accession#
BC008410Protein Accession#
AAH08410Gene Name
PMS1
Gene Alias
DKFZp781M0253, FLJ98259, HNPCC3, PMSL1, hPMS1
Gene Description
PMS1 postmeiotic segregation increased 1 (S. cerevisiae)
Omim ID
600258Gene Ontology
HyperlinkGene Summary
This gene encodes a protein belonging to the DNA mismatch repair mutL/hexB family. This protein is thought to be involved in the repair of DNA mismatches, and it can form heterodimers with MLH1, a known DNA mismatch repair protein. Mutations in this gene cause hereditary nonpolyposis colorectal cancer type 3 (HNPCC3) either alone or in combination with mutations in other genes involved in the HNPCC phenotype, which is also known as Lynch syndrome. [provided by RefSeq
Other Designations
human homolog of yeast mutL|mismatch repair gene PMSL1|postmeiotic segregation 1|rhabdomyosarcoma antigen MU-RMS-40.10B|rhabdomyosarcoma antigen MU-RMS-40.10E
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Interactome
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Disease
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