PMM2 monoclonal antibody (M02), clone 2A5
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Specifications
Product Description
Mouse monoclonal antibody raised against a full-length recombinant PMM2.
Immunogen
PMM2 (AAH08310, 1 a.a. ~ 246 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
MAAPGPALCLFDVDGTLTAPRQKITKEMDDFLQKLRQKIKIGVVGGSDFEKVQEQLGNDVVEKYDYVFPENGLVAYKDGKLLCRQNIQSHLGEALIQDLINYCLSYIAKIKLPKKRGTFIEFRNGMLNVSPIGRSCSQEERIEFYELDKKENIRQKFVADLRKEFAGKGLTFSIGGQISFDVFPDGWDKRYCLRHVENDGYKTIYFFGDKTMPGGNDHEIFTDPRTMGYSVTAPEDTRRICELLFS
Host
Mouse
Reactivity
Human
Isotype
IgG2b Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (52.8 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Cell lysate)
PMM2 monoclonal antibody (M02), clone 2A5. Western Blot analysis of PMM2 expression in K-562 ( Cat # L009V1 ).Western Blot (Recombinant protein)
ELISA
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Gene Info — PMM2
Entrez GeneID
5373GeneBank Accession#
BC008310Protein Accession#
AAH08310Gene Name
PMM2
Gene Alias
CDG1, CDG1a, CDGS
Gene Description
phosphomannomutase 2
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene catalyzes the isomerization of mannose 6-phosphate to mannose 1-phosphate, which is a precursor to GDP-mannose necessary for the synthesis of dolichol-P-oligosaccharides. Mutations in this gene have been shown to cause defects in glycoprotein biosynthesis, which manifests as carbohydrate-deficient glycoprotein syndrome type I. [provided by RefSeq
Other Designations
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Interactomes
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Pathways
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