PMM2 MaxPab rabbit polyclonal antibody (D01)
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human PMM2 protein.
Immunogen
PMM2 (NP_000294.1, 1 a.a. ~ 246 a.a) full-length human protein.
Sequence
MAAPGPALCLFDVDGTLTAPRQKITKEMDDFLQKLRQKIKIGVVGGSDFEKVQEQLGNDVVEKYDYVFPENGLVAYKDGKLLCRQNIQSHLGEALIQDLINYCLSYIAKIKLPKKRGTFIEFRNGMLNVSPIGRSCSQEERIEFYELDKKENIRQKFVADLRKEFAGKGLTFSIGGQISFDVFPDGWDKRYCLRHVENDGYKTIYFFGDKTMPGGNDHEIFTDPRTMGYSVTAPEDTRRICELLFS
Host
Rabbit
Reactivity
Human
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
No additive
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Immunoprecipitation
Immunoprecipitation of PMM2 transfected lysate using anti-PMM2 MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead, and immunoblotted with PMM2 MaxPab mouse polyclonal antibody (B01) (H00005373-B01). -
Gene Info — PMM2
Entrez GeneID
5373GeneBank Accession#
NM_000303.1Protein Accession#
NP_000294.1Gene Name
PMM2
Gene Alias
CDG1, CDG1a, CDGS
Gene Description
phosphomannomutase 2
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene catalyzes the isomerization of mannose 6-phosphate to mannose 1-phosphate, which is a precursor to GDP-mannose necessary for the synthesis of dolichol-P-oligosaccharides. Mutations in this gene have been shown to cause defects in glycoprotein biosynthesis, which manifests as carbohydrate-deficient glycoprotein syndrome type I. [provided by RefSeq
Other Designations
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Interactome
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Pathway
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