PMM2 MaxPab mouse polyclonal antibody (B01)
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human PMM2 protein.
Immunogen
PMM2 (NP_000294.1, 1 a.a. ~ 246 a.a) full-length human protein.
Sequence
MAAPGPALCLFDVDGTLTAPRQKITKEMDDFLQKLRQKIKIGVVGGSDFEKVQEQLGNDVVEKYDYVFPENGLVAYKDGKLLCRQNIQSHLGEALIQDLINYCLSYIAKIKLPKKRGTFIEFRNGMLNVSPIGRSCSQEERIEFYELDKKENIRQKFVADLRKEFAGKGLTFSIGGQISFDVFPDGWDKRYCLRHVENDGYKTIYFFGDKTMPGGNDHEIFTDPRTMGYSVTAPEDTRRICELLFS
Host
Mouse
Reactivity
Human
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
No additive
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Note
For IHC and IF applications, antibody purification with Protein A will be needed prior to use.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of PMM2 expression in transfected 293T cell line (H00005373-T01) by PMM2 MaxPab polyclonal antibody.
Lane 1: PMM2 transfected lysate(27.06 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — PMM2
Entrez GeneID
5373GeneBank Accession#
NM_000303.1Protein Accession#
NP_000294.1Gene Name
PMM2
Gene Alias
CDG1, CDG1a, CDGS
Gene Description
phosphomannomutase 2
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene catalyzes the isomerization of mannose 6-phosphate to mannose 1-phosphate, which is a precursor to GDP-mannose necessary for the synthesis of dolichol-P-oligosaccharides. Mutations in this gene have been shown to cause defects in glycoprotein biosynthesis, which manifests as carbohydrate-deficient glycoprotein syndrome type I. [provided by RefSeq
Other Designations
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Interactome
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Pathway
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