PLP1 293T Cell Transient Overexpression Lysate(Denatured)
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-PLP1 full-length
Host
Human
Theoretical MW (kDa)
30.1
Interspecies Antigen Sequence
Mouse (100); Rat (100)
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-PLP1 antibody (H00005354-D01P) by Western Blots.
SDS-PAGE Gel
PLP1 transfected lysate.
Western Blot
Lane 1: PLP1 transfected lysate ( 30.10 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — PLP1
Entrez GeneID
5354GeneBank Accession#
NM_000533Protein Accession#
NP_000524.3Gene Name
PLP1
Gene Alias
HLD1, MMPL, PLP, PLP/DM20, PMD, SPG2
Gene Description
proteolipid protein 1
Gene Ontology
HyperlinkGene Summary
This gene encodes a transmembrane proteolipid protein that is the predominant myelin protein present in the central nervous system. It may play a role in the compaction, stabilization, and maintenance of myelin sheaths, as well as in oligodendrocyte development and axonal survival. Mutations in this gene cause X-linked Pelizaeus-Merzbacher disease and spastic paraplegia type 2. Alternatively spliced transcript variants encoding distinct isoforms or having different 5' UTRs, have been identified for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000023761|OTTHUMP00000023762|lipophilin|major myelin proteolipid protein
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