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PLP1 Pre-design Chimera RNAi

  • Catalog # : H00005354-R02
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  • Specification
  • Product Description:
  • Homo sapiens proteolipid protein 1 (Pelizaeus-Merzbacher disease, spastic paraplegia 2, uncomplicated) (PLP1), transcript variant 2, mRNA.
  • Reactivity:
  • Human
  • Supplied Product:
  • DEPC water
  • Target Refseq:
  • NM_199478
  • Storage Instruction:
  • Store at -20°C, do not exceed 4 - 5 freeze-thaw cycles to ensure product integrity.
  • Note:
  • Position of the Chimera RNAi.

  • Publication Reference
  • Applications
  • RNAi Knockdown
  • Application Image
  • RNAi Knockdown
  • Gene Information
  • Entrez GeneID:
  • 5354
  • Gene Name:
  • PLP1
  • Gene Alias:
  • HLD1,MMPL,PLP,PLP/DM20,PMD,SPG2
  • Gene Description:
  • proteolipid protein 1
  • Gene Summary:
  • This gene encodes a transmembrane proteolipid protein that is the predominant myelin protein present in the central nervous system. It may play a role in the compaction, stabilization, and maintenance of myelin sheaths, as well as in oligodendrocyte development and axonal survival. Mutations in this gene cause X-linked Pelizaeus-Merzbacher disease and spastic paraplegia type 2. Alternatively spliced transcript variants encoding distinct isoforms or having different 5' UTRs, have been identified for this gene. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000023761,OTTHUMP00000023762,lipophilin,major myelin proteolipid protein
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