PLP1 monoclonal antibody (M05), clone 4H8

Catalog # H00005354-M05

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Size:100 ug
Price: USD $ 335.00
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Contact Info
  • +1-909-264-1399
    +1-909-992-0619
    Toll Free : +1-877-853-6098
  • +1-909-992-3401
Images
Sandwich ELISA (Recombinant protein)
Application

Sandwich ELISA (Recombinant protein)

Detection limit for recombinant GST tagged PLP1 is approximately 0.03ng/ml as a capture antibody.

QC Test

Western Blot detection against Immunogen (31.9 KDa) .

  • Specification

    Product Description

    Mouse monoclonal antibody raised against a partial recombinant PLP1.

    Immunogen

    PLP1 (NP_000524, 177 a.a. ~ 232 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

    Sequence

    YFNTWTTCQSIAFPSKTSASIGSLCADARMYGVLPWNAFPGKVCGSNLLSICKTAE

    Host

    Mouse

    Reactivity

    Human

    Interspecies Antigen Sequence

    Mouse (100); Rat (100)

    Isotype

    IgG2a Kappa

    Quality Control Testing

    Antibody Reactive Against Recombinant Protein.

    Western Blot detection against Immunogen (31.9 KDa) .

    Storage Buffer

    In 1x PBS, pH 7.4

    Storage Instruction

    Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

  • Applications

    Western Blot (Recombinant protein)

    Sandwich ELISA (Recombinant protein)

    Detection limit for recombinant GST tagged PLP1 is approximately 0.03ng/ml as a capture antibody.

    ELISA

  • Gene Info — PLP1

    Entrez GeneID

    5354

    GeneBank Accession#

    NM_000533

    Protein Accession#

    NP_000524

    Gene Name

    PLP1

    Gene Alias

    HLD1, MMPL, PLP, PLP/DM20, PMD, SPG2

    Gene Description

    proteolipid protein 1

    Omim ID

    300401 312080 312920

    Gene Ontology

    Hyperlink

    Gene Summary

    This gene encodes a transmembrane proteolipid protein that is the predominant myelin protein present in the central nervous system. It may play a role in the compaction, stabilization, and maintenance of myelin sheaths, as well as in oligodendrocyte development and axonal survival. Mutations in this gene cause X-linked Pelizaeus-Merzbacher disease and spastic paraplegia type 2. Alternatively spliced transcript variants encoding distinct isoforms or having different 5' UTRs, have been identified for this gene. [provided by RefSeq

    Other Designations

    OTTHUMP00000023761|OTTHUMP00000023762|lipophilin|major myelin proteolipid protein

  • Interactome
  • Disease
Contact Info
  • +1-909-264-1399
    +1-909-992-0619
    Toll Free : +1-877-853-6098
  • +1-909-992-3401
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