PLP1 MaxPab rabbit polyclonal antibody (D01)
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More Files
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human PLP1 protein.
Immunogen
PLP1 (NP_000524.3, 1 a.a. ~ 277 a.a) full-length human protein.
Sequence
MGLLECCARCLVGAPFASLVATGLCFFGVALFCGCGHEALTGTEKLIETYFSKNYQDYEYLINVIHAFQYVIYGTASFFFLYGALLLAEGFYTTGAVRQIFGDYKTTICGKGLSATVTGGQKGRGSRGQHQAHSLERVCHCLGKWLGHPDKFVGITYALTVVWLLVFACSAVPVYIYFNTWTTCQSIAFPSKTSASIGSLCADARMYGVLPWNAFPGKVCGSNLLSICKTAEFQMTFHLFIAAFVGAAATLVSLLTFMIAATYNFAVLKLMGRGTKF
Host
Rabbit
Reactivity
Human
Interspecies Antigen Sequence
Mouse (100); Rat (100)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
No additive
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of PLP1 expression in transfected 293T cell line (H00005354-T01) by PLP1 MaxPab polyclonal antibody.
Lane 1: PLP1 transfected lysate(30.10 KDa).
Lane 2: Non-transfected lysate.
Immunoprecipitation
Immunoprecipitation of PLP1 transfected lysate using anti-PLP1 MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead, and immunoblotted with PLP1 MaxPab rabbit polyclonal antibody (D01) (H00005354-D01). -
Gene Info — PLP1
Entrez GeneID
5354GeneBank Accession#
NM_000533Protein Accession#
NP_000524.3Gene Name
PLP1
Gene Alias
HLD1, MMPL, PLP, PLP/DM20, PMD, SPG2
Gene Description
proteolipid protein 1
Gene Ontology
HyperlinkGene Summary
This gene encodes a transmembrane proteolipid protein that is the predominant myelin protein present in the central nervous system. It may play a role in the compaction, stabilization, and maintenance of myelin sheaths, as well as in oligodendrocyte development and axonal survival. Mutations in this gene cause X-linked Pelizaeus-Merzbacher disease and spastic paraplegia type 2. Alternatively spliced transcript variants encoding distinct isoforms or having different 5' UTRs, have been identified for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000023761|OTTHUMP00000023762|lipophilin|major myelin proteolipid protein
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Interactome
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Disease
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