PLOD2 MaxPab rabbit polyclonal antibody (D01)
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More Files
- More Functions
Western Blot (Cell lysate)
PLOD2 MaxPab rabbit polyclonal antibody. Western Blot analysis of PLOD2 expression in HeLa.
Western Blot (Transfected lysate)
Western Blot analysis of PLOD2 expression in transfected 293T cell line (H00005352-T01) by PLOD2 MaxPab polyclonal antibody.
Lane 1: PLOD2 transfected lysate(87.10 KDa).
Lane 2: Non-transfected lysate.
Immunoprecipitation
Immunoprecipitation of PLOD2 transfected lysate using anti-PLOD2 MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead, and immunoblotted with PLOD2 MaxPab rabbit polyclonal antibody (D01) (H00005352-D01).
Immunofluorescence
Immunofluorescence of purified MaxPab antibody to PLOD2 on HeLa cell. [antibody concentration 30 ug/ml]
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human PLOD2 protein.
Immunogen
PLOD2 (NP_891988.1, 1 a.a. ~ 758 a.a) full-length human protein.
Sequence
MGGCTVKPQLLLLALVLHPWNPCLGADSEKPSSIPTDKLLVITVATKESDGFHRFMQSAKYFNYTVKVLGQGEEWRGGDGINSIGGGQKVRLMKEVMEHYADQDDLVVMFTECFDVIFAGGPEEVLKKFQKANHKVVFAADGILWPDKRLADKYPVVHIGKRYLNSGGFIGYAPYVNRIVQQWNLQDNDDDQLFYTKVYIDPLKREAINITLDHKCKIFQTLNGAVDEVVLKFENGKARAKNTFYETLPVAINGNGPTKILLNYFGNYVPNSWTQDNGCTLCEFDTVDLSAVDVHPNVSIGVFIEQPTPFLPRFLDILLTLDYPKEALKLFIHNKEVYHEKDIKVFFDKAKHEIKTIKIVGPEENLSQAEARNMGMDFCRQDEKCDYYFSVDADVVLTNPRTLKILIEQNRKIIAPLVTRHGKLWSNFWGALSPDGYYARSEDYVDIVQGNRVGVWNVPYMANVYLIKGKTLRSEMNERNYFVRDKLDPDMALCRNAREMTLQREKDSPTPETFQMLSPPKGVFMYISNRHEFGRLLSTANYNTSHYNNDLWQIFENPVDWKEKYINRDYSKIFTENIVEQPCPDVFWFPIFSEKACDELVEEMEHYGKWSGGKHHDSRISGGYENVPTDDIHMKQVDLENVWLHFIREFIAPVTLKVFAGYYTKGFALLNFVVKYSPERQRSLRPHHDASTFTINIALNNVGEDFQGGGCKFLRYNCSIESPRKGWSFMHPGRLTHLHEGLPVKNGTRYIAVSFIDP
Host
Rabbit
Reactivity
Human
Interspecies Antigen Sequence
Mouse (91); Rat (91)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
No additive
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Cell lysate)
PLOD2 MaxPab rabbit polyclonal antibody. Western Blot analysis of PLOD2 expression in HeLa.Western Blot (Transfected lysate)
Western Blot analysis of PLOD2 expression in transfected 293T cell line (H00005352-T01) by PLOD2 MaxPab polyclonal antibody.
Lane 1: PLOD2 transfected lysate(87.10 KDa).
Lane 2: Non-transfected lysate.
Immunoprecipitation
Immunoprecipitation of PLOD2 transfected lysate using anti-PLOD2 MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead, and immunoblotted with PLOD2 MaxPab rabbit polyclonal antibody (D01) (H00005352-D01).Immunofluorescence
Immunofluorescence of purified MaxPab antibody to PLOD2 on HeLa cell. [antibody concentration 30 ug/ml] -
Gene Info — PLOD2
Entrez GeneID
5352GeneBank Accession#
NM_182943.2Protein Accession#
NP_891988.1Gene Name
PLOD2
Gene Alias
LH2, TLH
Gene Description
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a membrane-bound homodimeric enzyme that is localized to the cisternae of the rough endoplasmic reticulum. The enzyme (cofactors iron and ascorbate) catalyzes the hydroxylation of lysyl residues in collagen-like peptides. The resultant hydroxylysyl groups are attachment sites for carbohydrates in collagen and thus are critical for the stability of intermolecular crosslinks. Some patients with Ehlers-Danlos syndrome type VIB have deficiencies in lysyl hydroxylase activity. Mutations in the coding region of this gene are associated with Bruck syndrome. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq
Other Designations
lysine hydroxylase 2|lysyl hydroxylase 2|telopeptide lysyl hydroxylase
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Interactome
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Pathway
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Disease
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Publication Reference
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KDM1A regulated the osteo/dentinogenic differentiation process of the stem cells of the apical papilla via binding with PLOD2.
Wang L, Yang H, Lin X, Cao Y, Gao P, Zheng Y, Fan Z.
Cell proliferation 2018 Aug; 51(4):e12459.
Application：WB-Tr, Human, Human apical papilla stem cells.
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KDM1A regulated the osteo/dentinogenic differentiation process of the stem cells of the apical papilla via binding with PLOD2.
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