PLOD1 DNAxPab
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Specification
Product Description
Rabbit polyclonal antibody raised against a partial-length human PLOD1 DNA using DNAx™ Immune technology.
Technology
Immunogen
Extracellular membrane domain (ECD) human DNA
Host
Rabbit
Reactivity
Human
Purification
Protein A
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Immunofluorescence (Transfected cell)
Flow Cytometry (Transfected cell)
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Gene Info — PLOD1
Entrez GeneID
5351GeneBank Accession#
NM_000302.2Protein Accession#
NP_000293.2Gene Name
PLOD1
Gene Alias
FLJ42041, LH, LH1, LLH, PLOD
Gene Description
procollagen-lysine 1, 2-oxoglutarate 5-dioxygenase 1
Gene Ontology
HyperlinkGene Summary
Lysyl hydroxylase is a membrane-bound homodimeric protein localized to the cisternae of the endoplasmic reticulum. The enzyme (cofactors iron and ascorbate) catalyzes the hydroxylation of lysyl residues in collagen-like peptides. The resultant hydroxylysyl groups are attachment sites for carbohydrates in collagen and thus are critical for the stability of intermolecular crosslinks. Some patients with Ehlers-Danlos syndrome type VI have deficiencies in lysyl hydroxylase activity. [provided by RefSeq
Other Designations
OTTHUMP00000002512|lysine hydroxylase|lysyl hydroxylase|lysyl hydroxylase 1|procollagen-lysine, 2-oxoglutarate 5-dioxygenase
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Interactome
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Pathway
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Disease
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