PLOD1 polyclonal antibody (A01)
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Specification
Product Description
Mouse polyclonal antibody raised against a partial recombinant PLOD1.
Immunogen
PLOD1 (NP_000293, 19 a.a. ~ 114 a.a) partial recombinant protein with GST tag.
Sequence
KGDAKPEDNLLVLTVATKETEGFRRFKRSAQFFNYKIQALGLGEDWNVEKGTSAGGGQKVRLLKKALEKHADKEDLVILFADSYDVLFASGPRELL
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (88); Rat (85)
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (36.67 KDa) .
Storage Buffer
50 % glycerol
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
ELISA
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Gene Info — PLOD1
Entrez GeneID
5351GeneBank Accession#
NM_000302Protein Accession#
NP_000293Gene Name
PLOD1
Gene Alias
FLJ42041, LH, LH1, LLH, PLOD
Gene Description
procollagen-lysine 1, 2-oxoglutarate 5-dioxygenase 1
Gene Ontology
HyperlinkGene Summary
Lysyl hydroxylase is a membrane-bound homodimeric protein localized to the cisternae of the endoplasmic reticulum. The enzyme (cofactors iron and ascorbate) catalyzes the hydroxylation of lysyl residues in collagen-like peptides. The resultant hydroxylysyl groups are attachment sites for carbohydrates in collagen and thus are critical for the stability of intermolecular crosslinks. Some patients with Ehlers-Danlos syndrome type VI have deficiencies in lysyl hydroxylase activity. [provided by RefSeq
Other Designations
OTTHUMP00000002512|lysine hydroxylase|lysyl hydroxylase|lysyl hydroxylase 1|procollagen-lysine, 2-oxoglutarate 5-dioxygenase
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Interactome
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Pathway
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Disease
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