SERPINF2 293T Cell Transient Overexpression Lysate(Denatured)
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-SERPINF2 full-length
Host
Human
Theoretical MW (kDa)
54.12
Interspecies Antigen Sequence
Mouse (74); Rat (73)
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-SERPINF2 antibody (H00005345-B01) by Western Blots.
SDS-PAGE Gel
SERPINF2 transfected lysate.
Western Blot
Lane 1: SERPINF2 transfected lysate ( 54.12 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — SERPINF2
Entrez GeneID
5345GeneBank Accession#
BC031592.1Protein Accession#
AAH31592.1Gene Name
SERPINF2
Gene Alias
A2AP, AAP, ALPHA-2-PI, API, PLI
Gene Description
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2
Omim ID
262850Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the serpin family of serine protease inhibitors. The protein is a major inhibitor of plasmin, which degrades fibrin and various other proteins. Consequently, the proper function of this gene has a major role in regulating the blood clotting pathway. Mutations in this gene result in alpha-2-plasmin inhibitor deficiency, which is characterized by severe hemorrhagic diathesis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
alpha-2-antiplasmin|alpha-2-plasmin inhibitor|serine (or cysteine) proteinase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2
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Interactome
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Pathway
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Disease
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