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PLAT 293T Cell Transient Overexpression Lysate(Denatured)

  • Catalog # : H00005327-T01
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  • Specification
  • Transfected Cell Line:
  • 293T
  • Plasmid:
  • pCMV-PLAT full-length
  • Host:
  • Human
  • Theoretical MW (kDa):
  • 62.9
  • Quality Control Testing:
  • Transient overexpression cell lysate was tested with Anti-PLAT antibody (H00005327-B01) by Western Blots.
    SDS-PAGE Gel
    QC Testing of H00005327-T01
    PLAT transfected lysate.
    Western Blot
    QC Testing of H00005327-T01
    Lane 1: PLAT transfected lysate ( 62.9 KDa)
    Lane 2: Non-transfected lysate.
  • Storage Buffer:
  • 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
  • Storage Instruction:
  • Store at -80°C. Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Western Blot
  • Application Image
  • Western Blot
  • Gene Information
  • Entrez GeneID:
  • 5327
  • Gene Name:
  • PLAT
  • Gene Alias:
  • DKFZp686I03148,T-PA,TPA
  • Gene Description:
  • plasminogen activator, tissue
  • Gene Summary:
  • This gene encodes tissue-type plasminogen activator, a secreted serine protease which converts the proenzyme plasminogen to plasmin, a fibrinolytic enzyme. Tissue-type plasminogen activator is synthesized as a single chain which is cleaved by plasmin to a two chain disulfide linked protein. This enzyme plays a role in cell migration and tissue remodeling. Increased enzymatic activity causes hyperfibrinolysis, which manifests as excessive bleeding; decreased activity leads to hypofibrinolysis which can result in thrombosis or embolism. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms. [provided by RefSeq
  • Other Designations:
  • alteplase,plasminogen activator, tissue type,reteplase,t-plasminogen activator,tissue plasminogen activator (t-PA)
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