PLA2G5 DNAxPab
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human PLA2G5 DNA using DNAx™ Immune technology.
Technology
Immunogen
Full-length human DNA
Sequence
MKGLLPLAWFLACSVPAVQGGLLDLKSMIEKVTGKNALTNYGFYGCYCGWGGRGTPKDGTDWCCWAHDHCYGRLEEKGCNIRTQSYKYRFAWGVVTCEPGPFCHVNLCACDRKLVYCLKRNLRSYNPQYQYFPNILCS
Host
Rabbit
Reactivity
Human
Purification
Protein A
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Immunofluorescence (Transfected cell)
Flow Cytometry (Transfected cell)
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Gene Info — PLA2G5
Entrez GeneID
5322GeneBank Accession#
NM_000929.1Protein Accession#
NP_000920.1Gene Name
PLA2G5
Gene Alias
DKFZp686C2294, GV-PLA2, MGC46205, PLA2-10, hVPLA(2)
Gene Description
phospholipase A2, group V
Omim ID
601192Gene Ontology
HyperlinkGene Summary
This gene is a member of the secretory phospholipase A2 family. It is located in a tightly-linked cluster of secretory phospholipase A2 genes on chromosome 1. The encoded enzyme catalyzes the hydrolysis of membrane phospholipids to generate lysophospholipids and free fatty acids including arachidonic acid. It preferentially hydrolyzes linoleoyl-containing phosphatidylcholine substrates. Secretion of this enzyme is thought to induce inflammatory responses in neighboring cells. Alternatively spliced transcript variants have been found, but their full-length nature has not been determined. [provided by RefSeq
Other Designations
Ca2+-dependent phospholipase A2|OTTHUMP00000002785|OTTHUMP00000044655|phosphatidylcholine 2-acylhydrolase
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Interactome
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Disease
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