PLA2G5 (Human) Recombinant Protein (P01)
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Specification
Product Description
Human PLA2G5 full-length ORF ( NP_000920.1, 1 a.a. - 138 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MKGLLPLAWFLACSVPAVQGGLLDLKSMIEKVTGKNALTNYGFYGCYCGWGGRGTPKDGTDWCCWAHDHCYGRLEEKGCNIRTQSYKYRFAWGVVTCEPGPFCHVNLCACDRKLVYCLKRNLRSYNPQYQYFPNILCS
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
42.1
Interspecies Antigen Sequence
Mouse (78); Rat (78)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — PLA2G5
Entrez GeneID
5322GeneBank Accession#
NM_000929.1Protein Accession#
NP_000920.1Gene Name
PLA2G5
Gene Alias
DKFZp686C2294, GV-PLA2, MGC46205, PLA2-10, hVPLA(2)
Gene Description
phospholipase A2, group V
Omim ID
601192Gene Ontology
HyperlinkGene Summary
This gene is a member of the secretory phospholipase A2 family. It is located in a tightly-linked cluster of secretory phospholipase A2 genes on chromosome 1. The encoded enzyme catalyzes the hydrolysis of membrane phospholipids to generate lysophospholipids and free fatty acids including arachidonic acid. It preferentially hydrolyzes linoleoyl-containing phosphatidylcholine substrates. Secretion of this enzyme is thought to induce inflammatory responses in neighboring cells. Alternatively spliced transcript variants have been found, but their full-length nature has not been determined. [provided by RefSeq
Other Designations
Ca2+-dependent phospholipase A2|OTTHUMP00000002785|OTTHUMP00000044655|phosphatidylcholine 2-acylhydrolase
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Interactome
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