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Last updated: 2017/11/12

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PLA2G5 rabbit monoclonal antibody

  • Catalog # : H00005322-K
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against a human PLA2G5 peptide using ARM Technology.
  • Immunogen:
  • A synthetic peptide of human PLA2G5 is used for rabbit immunization.
    Customer or Abnova will decide on the preferred peptide sequence.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Purification:
  • Protein A
  • Isotype:
  • IgG
  • Quality Control Testing:
  • Antibody reactive against human PLA2G5 peptide by ELISA and mammalian transfected lysate by Western Blot.
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Note:
  • 1. Customer may provide cell or tissue lysate for antibody screening.
    2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.
  • Library Construction:
  • Non-fusion antibody library from rabbit spleen (ARM Technology).
  • Expression:
  • Overexpression vector and transfection into 293H cell line.
  • Deliverable:
  • Up to three rabbit IgG clones of 1 mg each will be delivered to customer.
  • Applications
  • ELISA
  • Application Image
  • Western Blot (Transfected lysate)
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 5322
  • Gene Name:
  • PLA2G5
  • Gene Alias:
  • DKFZp686C2294,GV-PLA2,MGC46205,PLA2-10,hVPLA(2)
  • Gene Description:
  • phospholipase A2, group V
  • Gene Summary:
  • This gene is a member of the secretory phospholipase A2 family. It is located in a tightly-linked cluster of secretory phospholipase A2 genes on chromosome 1. The encoded enzyme catalyzes the hydrolysis of membrane phospholipids to generate lysophospholipids and free fatty acids including arachidonic acid. It preferentially hydrolyzes linoleoyl-containing phosphatidylcholine substrates. Secretion of this enzyme is thought to induce inflammatory responses in neighboring cells. Alternatively spliced transcript variants have been found, but their full-length nature has not been determined. [provided by RefSeq
  • Other Designations:
  • Ca2+-dependent phospholipase A2,OTTHUMP00000002785,OTTHUMP00000044655,phosphatidylcholine 2-acylhydrolase
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