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PLA2G4A Pre-design Chimera RNAi

  • Catalog # : H00005321-R01
  • Visit Frequency :
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  • Specification
  • Product Description:
  • Homo sapiens phospholipase A2, group IVA (cytosolic, calcium-dependent) (PLA2G4A), mRNA.
  • Reactivity:
  • Human
  • Supplied Product:
  • DEPC water
  • Target Refseq:
  • NM_024420
  • Storage Instruction:
  • Store at -20°C, do not exceed 4 - 5 freeze-thaw cycles to ensure product integrity.
  • Note:
  • Position of the Chimera RNAi.

  • Publication Reference
  • Applications
  • RNAi Knockdown
  • Application Image
  • RNAi Knockdown
  • Gene Information
  • Entrez GeneID:
  • 5321
  • Gene Name:
  • PLA2G4A
  • Gene Alias:
  • MGC126350,PLA2G4,cPLA2-alpha
  • Gene Description:
  • phospholipase A2, group IVA (cytosolic, calcium-dependent)
  • Gene Summary:
  • This gene encodes a member of the cytosolic phospholipase A2 group IV family. The enzyme catalyzes the hydrolysis of membrane phospholipids to release arachidonic acid which is subsequently metabolized into eicosanoids. Eicosanoids, including prostaglandins and leukotrienes, are lipid-based cellular hormones that regulate hemodynamics, inflammatory responses, and other intracellular pathways. The hydrolysis reaction also produces lysophospholipids that are converted into platelet-activating factor. The enzyme is activated by increased intracellular Ca(2+) levels and phosphorylation, resulting in its translocation from the cytosol and nucleus to perinuclear membrane vesicles. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000033543,calcium-dependent phospholipid-binding protein,cytosolic phospholipase A2, group IVA,lysophospholipase,phosphatidylcholine 2-acylhydrolase
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