PLA2G2A (Human) Recombinant Protein (P01)
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Specification
Product Description
Human PLA2G2A full-length ORF ( AAH05919.1, 1 a.a. - 144 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MKTLLLLAVIMIFGLLQAHGNLVNFHRMIKLTTGKEAALSYGFYGCHCGVGGRGSPKDATDRCCVTHDCCYKRLEKRGCGTKFLSYKFSNSGSRITCAKQDSCRSQLCECDKAAATCSARNKTTYNKKYQYYSNKHCRGSTPRC
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
42.5
Interspecies Antigen Sequence
Rat (71)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — PLA2G2A
Entrez GeneID
5320GeneBank Accession#
BC005919.1Protein Accession#
AAH05919.1Gene Name
PLA2G2A
Gene Alias
MOM1, PLA2, PLA2B, PLA2L, PLA2S, PLAS1, sPLA2
Gene Description
phospholipase A2, group IIA (platelets, synovial fluid)
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the phospholipase A2 family (PLA2). PLA2s constitute a diverse family of enzymes with respect to sequence, function, localization, and divalent cation requirements. This gene product belongs to group II, which contains secreted form of PLA2, an extracellular enzyme that has a low molecular mass and requires calcium ions for catalysis. It catalyzes the hydrolysis of the sn-2 fatty acid acyl ester bond of phosphoglycerides, releasing free fatty acids and lysophospholipids, and thought to participate in the regulation of the phospholipid metabolism in biomembranes. Several alternatively spliced transcript variants with different 5' UTRs have been found for this gene
Other Designations
OTTHUMP00000002786|phosphatidylcholine 2-acylhydrolase|phospholipase A2, group IIA|synovial phospholipase-A2
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