PLA2G2A monoclonal antibody (M01), clone 2E8
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Specification
Product Description
Mouse monoclonal antibody raised against a full-length recombinant PLA2G2A.
Immunogen
PLA2G2A (AAH05919.1, 1 a.a. ~ 144 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
MKTLLLLAVIMIFGLLQAHGNLVNFHRMIKLTTGKEAALSYGFYGCHCGVGGRGSPKDATDRCCVTHDCCYKRLEKRGCGTKFLSYKFSNSGSRITCAKQDSCRSQLCECDKAAATCSARNKTTYNKKYQYYSNKHCRGSTPRC
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Rat (71)
Isotype
IgG1 Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged PLA2G2A is 0.1 ng/ml as a capture antibody.ELISA
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Gene Info — PLA2G2A
Entrez GeneID
5320GeneBank Accession#
BC005919.1Protein Accession#
AAH05919.1Gene Name
PLA2G2A
Gene Alias
MOM1, PLA2, PLA2B, PLA2L, PLA2S, PLAS1, sPLA2
Gene Description
phospholipase A2, group IIA (platelets, synovial fluid)
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the phospholipase A2 family (PLA2). PLA2s constitute a diverse family of enzymes with respect to sequence, function, localization, and divalent cation requirements. This gene product belongs to group II, which contains secreted form of PLA2, an extracellular enzyme that has a low molecular mass and requires calcium ions for catalysis. It catalyzes the hydrolysis of the sn-2 fatty acid acyl ester bond of phosphoglycerides, releasing free fatty acids and lysophospholipids, and thought to participate in the regulation of the phospholipid metabolism in biomembranes. Several alternatively spliced transcript variants with different 5' UTRs have been found for this gene
Other Designations
OTTHUMP00000002786|phosphatidylcholine 2-acylhydrolase|phospholipase A2, group IIA|synovial phospholipase-A2
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Interactome
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